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National Open University Exam Past Question – CHM 318 October, 2013 Examination

NATIONAL OPEN UNIVERSITY OF NIGERIA CHM 318 Natural Products Chemistry I

14/16, Ahmadu Bello Way, Victoria Island

 

SCHOOL OF SCIENCE AND TECHNOLOGY October, 2013 Examination

 

Course Code: CHM 318

 

Course Title:  Natural Products Chemistry I INSTRUCTION: Answer any 4 questions.            2 HOURS

 

 

1. (a) Write a short note on Steroids

 

(b) Explain Steroid Biosynthesis

(7½ marks). (10 marks).
 

 

2.

 

 

(a) What are terpenes.

 

 

(3marks).

   

(b) Discuss 5 major classes of terpenes

 

(10marks).

   

(c) Draw the structure of a named terpene

 

(4.5marks).

 

 

3.

 

 

(a) Write a short note on Alkaloids?

 

 

(5marks).

   

(b) Explain concisely the applications of Alkaloids in Medicine

 

(12½ marks).

 

 

 

4.   (a) With the aid of a well-labeled diagram, describe the MEVALONATE Pathway?

(14½ marks).

  (b) Name 2 drugs that target the Mevalonate Pathway (3 marks).
 

 

5.

 

 

(a) Discuss the properties of Alkaloids

 

 

(11½ marks).

   

(b) Draw the structures of 2 named Alkaloids

 

(6 marks).

 

 

6.

 

 

(a) Discuss five examples of dimeric alkaloids

 

 

(12½ marks).

   

(b) What do you understand by the term steroidogenesis?

 

(5 marks).

 

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